Archive for August, 2011

Take a look at one aspect of parkinson’s disease prognosis through the eyes of this video maker.

In this video blog, Kapil D. Sethi, MD, discusses the limitations of levodopa therapy in controlling symptoms of Parkinson’s disease.
Video Rating: 4 / 5

Technorati Tags: disease, Levodopa, Parkinsons, symptoms, Unresponsive

Cannabis & Parkinson Disease

Videos, such as that shown here, are an excellent way to understand the subject of parkinson’s disease stages.

Cannabis & Parkinson Disease Tikun Olam – Medical Cannabis in Israel

Technorati Tags: Cannabis, disease, Parkinson

Vitamin D and Parkinson’s Disease

Watch the video below and then please leave a comment to let we know what you thought about it.

A lack of Vitamin D can contribute to many diseases, including parkinson’s
Video Rating: 5 / 5

Technorati Tags: disease, Parkinsons, Vitamin

A question from Dogstar Lone Crusader of the Clone Apocalypse: How much do you think the Vatican paid that nun to pretend to have had Parkinson’s disease?
Just so that they could canonise John-Paul II.

Best answer:

Answer by The Resurrectionist
Probably not much. Plenty of religious nuts are more than willing to lie simply to try justify their own faith.

What do you think? Leave you answer below!

Technorati Tags: disease, much, paid, Parkinsons, pretend, think, Vatican

Parkinson’s Disease

Take a look at one aspect of parkinson’s disease treatment through the eyes of this video maker.

a little cartoon about parkinson’s disease
Video Rating: 5 / 5

Technorati Tags: disease, Parkinsons

Another great video on the topic of parkinson’s disease symptoms is included and we would welcome your comments once you have watched it.

Deep Brain Stimulation surgery can offset many of the symptoms of Parkinson’s Disease for many patients. Dr. Ken Follett, chief of neurosurgery at The Nebraska Medical Center explains how the surgery works and some of the successes he’s seen with Parkinson’s patients. The Nebraska Medical Center was named one of America’s Top 50 hospitals for neurosurgery by US News and World Report. For more information, call 1-800-922-0000 or visit www.nebraskamed.com.

Technorati Tags: center, disease, medical, Nebraska, Parkinsons, surgery

A question asked by anonymous: Dopamine: please explain endogenous and exogenous and some diseases and treatments?
Dopamine is a neurotransmitter that I really don’t understand as much as other NTs because of its varied implications and medication forms. For example, I have a hard time understanding the reason for its varied implications in many different diseases/conditions, such as the use of L-Dopa for Parkinson’s all the way to use of Da in the IV form for shock. And the implication of Da in cocaine addiction.

I’d appreciate any explanation. The more detailed and technical, the better. Thank you. I’ve never studied biochemistry or any subject like this, just pharmacology and pathophysiology.
One time I was trying to convince a person that cocaine use was harmful and I knew it had something to do with Da receptors, but I wasn’t sure so I didn’t mention anything in physiological detail…
You are a nice doc! Thanks. Even if no one else would bother with this question, your reply is complete and sufficient. Thanks!!!

The top answer:

Answer by nicedoc
Dopamine has a wide variety of functions physiologically. It’s a neurotransmitter heavily involved in control of motor function (in the extrapyramidal system). Diseases that deal with dopamine deficient states like Parkinson’s disease lead to slowness of movement and resting tremor. This can also occur as a side effect of long term of antipsychotics which block dopamine receptors and hence such patients can look like they have Parkinson’s (in fact we call this drug-induced parkinsonism or DIP).

Dopamine also figures prominently in behavior particularly in risk-reward pathway (like the rush one gets when winning a big hand while gambling for example), obsessive-compulsiveness and manic states. Hence drugs of abuse like cocaine and amphetamines have their pleasurable effect by modulating dopaminergic systems (cocaine for example blocks the reuptake of dopamine among other monoamines, thus making dopamine and thus its effects last longer in the nervous system). Likewise, treatments for Parkinson’s disease, particularly dopamine agonists can have compulsive behaviors such as excessive gambling/shopping and obessive-compulsive behavoirs as side effects.

Dopamine also has effects on blood pressure; interestingly at low doses it can lower blood pressure but at higher doses it can increase blood pressure (and is used medically for this reason as a vasopressor). However, as dopamine is broken down very quickly in the peripheral system, it’s unlikely it actually plays a real role in blood pressure control under normal conditions.

When people talk about endogenous vs exogenous dopamine, it just refers to whether the dopamine comes from existing physiologic stores (endogenous) or from an outside source, like a medication (exogenous). Thus you could say cocaine works by enhancing the effects of endogenous dopamine while Sinemet, a Parkinson’s disease drug , works by supplying exogenous dopamine.

Hope this helps somewhat.

What do you think? Leave you answer below!

Technorati Tags: Diseases, Dopamine, endogenous, exogenous, explain, Please, some, treatments

A great visual look at the subject of parkinson’s disease prognosis.

maureen speaks a bit on the ‘mission’ behind these non scripted ‘in the moment’ videos that aim to create awareness of the mysterious illnesses rooted in the brain, such as parkinson’s disease which she has lived with for 13 years. here is the outline for a foundation that will donate funds to help the living maintain an optimum quality of life… NOW! we are creating a place as aids and cancer groups have done to concentrate not only on cures. please, take that money that’s going to buy a plaque with your name on it, to live across eternity on a hospital wall, AND/OR, share supporting the search for a cure and buy someone’s groceries, pay past due bills to help ‘catch up’, provide supplements … ad infinitum. thank you again for watching. spread the word ! BE BOLD AND KEEP YOUR BOD IN MOTION !

Technorati Tags: cure, disease, funds, life, maintain, Parkinsons, pd's, quality, symptoms, there

A question asked by Bobsyouruncle: Is there a way to reduce signs of Parkinson’s disease at its early stages?
What are the signs of it at the early stages?

Selected answer:

Answer by erbs2005
Symptoms may be mild at first. For instance, the patient may have a mild tremor or a slight feeling that one leg or foot is stiff and dragging.

There are no clear risk factors or preventions for PD. Central body obesity may increase the risk. Some studies have found that coffee drinking or hormone replacement therapy (HRT) in postmenopausal women may decrease the risk of PD. However, heavy coffee drinking in combination with HRT appears to increase the risk of Parkinson’s disease.

Agree or disagree? Leave your own thoughts below.

Technorati Tags: disease, early, Parkinsons, reduce, Signs, stages, there

The other day I ran across this video about parkinson’s disease treatment which I think you will probably find of interest.

www.medra.com – Breakthrough Stem Cell treatment for Parkinson’s
Video Rating: 0 / 5

Technorati Tags: Gains, hand, Medra, Mobility, more, Parkinsons, patient, Right

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