I Am a Male 52 Years Old With Parkinson’s Disease. Periodically During the Day I Start Sweating Profusely?
Saturday, May 14th, 2011 at
7:35 pm
A question asked by K: I am a male 52 years old with Parkinson’s disease. Periodically during the day I start sweating profusely?
whether I am just eating or walking thru the mall (it seems when my adrenaline is high) does anyone know what causes this ?
My chosen answer:
Answer by Natou67
It might have nothing to do with Parkinson’s disease. I wold check into what is called HYPERHIDROSIS. Talk to your doctor about this
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Tagged with: disease • during • male • Parkinsons • Periodically • profusely • start • sweating • years
Filed under: Parkinsons
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Excessive sweating (hyperhidrosis) is a secondary symptom of Parkinson’s disease. While it is possible for the cause to be other than your PD, the chances are it is related either to the disease or as a side effect of a medication you are taking. As you know, skin changes and problems, dry skin, oily skin, sweating too little or too much are all symptoms of PD.
http://www.neurologychannel.com/parkinsonsdisease/symptoms.shtml
Not knowing what your medications are, it is possible that sweating occurs because of “wearing off” of medications. Depending upon what you are eating – higher animal protein which can interfer with levodopa – it is possible that the act of eating triggers an interference which causes the wearing off effect. The study abstract linked below found: “that sweating fluctuates in conjunction with wearing-off phenomenon.”
http://www.ncbi.nlm.nih.gov/pubmed/17357129
The article at the next site is very helpful and explains what you want to know. In it you will also find some suggestions: drinking plenty of fluids and adjusting medications. This is a problem that you can discuss with your neurologist. If you are on levodopa/carbidopa, you might want a controled-release version. As a matter of fact, more controlled release or timed release forms are being developed now to alleviate wearing off times. The article also suggests a COMT addition. You might want to discuss Stalevo with your doctor.
http://pdring.com/skin-diseases-irritation-in-parkinsons-disease.htm
Hyperhydrosis itself is sweating beyond the body’s need to cool itself. Certainly stress or tension can cause sweating as can exercise which would probably include eating.
http://en.wikipedia.org/wiki/Hyperhidrosis
So take a look at the sympathetic nervous system to see its role in persipration and adrenaline:
http://www.merck.com/mmhe/sec06/ch098666/ch098666a.html
http://en.wikipedia.org/wiki/Sympathetic_nervous_system
Occasionally anticholinergics are used to block the acetylcholine receptors in order to attain a better homeostasis between the diminished dopamine firing and acetylcholine. I wouldn’t have my husband who has PD ask his doctor for an anticholinergic unless there were no other less risky solutions.
additional reading:
http://www3.interscience.wiley.com/journal/105560467/abstract?CRETRY=1&SRETRY=0
http://www.springerlink.com/content/xp971234581wg4u5/
http://cat.inist.fr/?aModele=afficheN&cpsidt=18263884