A question asked by aju051000: What causes the loss of dopamine in your brain that leads to Parkinson’s Disease?
Most comprehensive answer:
Answer by Keith R No one knows what the actual cause of Parkinson’s is. I know this sounds simple, but the loss of dopamine is caused by the loss of dopamine producing neurons in the substantia nigra.
A question asked by tim_ume: Why exactly causes brain cells to die in Parkinson’s disease?
I know it has got to do with age, but why exactly do the brain cells die and what is the relation between age and dying of many brain cells almost at the same time?
Best answer:
Answer by TMB When brain cells die in the substantia nigra it doesn’t release enough dopamine. Without dopamine, signals cannot travel from SN brain cells to cells in other parts of the brain. The “instructions” that brain cells need to move muscles do not reach their targets. Eventually, walking, writing, reaching for objects, and other basic movements do not occur correctly. Muscular movement becomes weaker and more erratic.
Researchers have not yet discovered the basic cause of Parkinson’s disease. They do not know why SN brain cells lose the ability to produce dopamine. Some scientists think that the disease is hereditary. They believe that PD can be passed down from generation to generation. Other researchers think that environmental factors may be to blame. They suspect that certain chemicals in the world around us get into the human body and damage SN brain cells.
Chronic:
Recurring frequently or lasting a long time.
Dopamine:
A neurotransmitter that helps send signals that control movement.
Neurotransmitter:
A chemical that helps transmit electrical signals from one brain cell to another.
Substantia nigra:
A region of the brain that controls movement.
Question posed by Ch0c0-Addict: What is Parkinson’s disease? and what causes it?
The best answer:
Answer by Chad R Parkinsons Disease is a nerological disease and it has many causes some can be genitical and some can be cause by to many blows to the head or many other brain problems
A question from Kelly C: dopamine in parkinson’s disease causes what?
The best answer:
Answer by anpianomd Dopamine is one of the neurotransmitters that is utilized in the brain. In Parkinson’s Disease, there is a decrease in the production of dopamine due to the degeneration of the cells that produce them (found in the striata nigra). The goals of treatment therefore is to increase dopamine which maybe approached by using drugs which stimulate more production (dopamine agonists) or to replace dopamine (Levodopa/Carbidopa combination). Both medicines have their own side effects. See a neurologist for further management
A question from Kelly C: dopamine in parkinson’s disease causes what?
The best answer:
Answer by anpianomd Dopamine is one of the neurotransmitters that is utilized in the brain. In Parkinson’s Disease, there is a decrease in the production of dopamine due to the degeneration of the cells that produce them (found in the striata nigra). The goals of treatment therefore is to increase dopamine which maybe approached by using drugs which stimulate more production (dopamine agonists) or to replace dopamine (Levodopa/Carbidopa combination). Both medicines have their own side effects. See a neurologist for further management
