The other day I ran across this video about parkinson’s disease treatment which I think you will probably find of interest.

www.medra.com – Breakthrough Stem Cell treatment for Parkinson’s
Video Rating: 0 / 5

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Question posed by Huey Freeman: your patient with parkinson’s disease is taking metoclopramide for GERD.?
Which statement is false.
a. the frequency of this metoclopramide causing extrapyramidal symptoms and depressions is highest in those with history of mental illness, children ans older adults.
b. this medication may cause drowsiness, confusion or depression
c. This medication is first line treatment for GERD.
d. this drug should be used with great caution in persons with Parkinson’s Disease as it blocks dopamine receptors and may worsen symptoms of PD.

The No 1 answer:

Answer by Mags
c. Dopamine antagonists are seldom used for Parkinson’s disease any longer. They are used as anti-psychotics for PD primarily. They most certainly wouldn’t be a first line medication for GERD in a PD patient.

That said there might be some benefit to the action of metoclopramide in the case of the common digestive issues of PD as it does increase muscle contraction of the upper GI tract.

a) is true
b) is also a precautionary warning
d) is another warning about dopamine antagonists which bind to the dopamine receptors but do not stimulate them. Because the PD medication (drug interactions) of this patient is unknown in the question, the statemtment is also true.

Take a look at this abstract to see if it provides additional insight into the correct answer.

http://www3.interscience.wiley.com/journal/118506024/abstract?CRETRY=1&SRETRY=0

While there might be a reason for prescribing it, it would never be a first line treatment for a PD patient as defined in the question.

Whether you agree or disagree, why not leave your own thoughts below.

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A question from Addicted to Yahoo! Answers: What are cancer treatment options when the patient also has Parkinson’s Disease?
A dear friend of mine has Stage 3A lung cancer, but also has Parkinson’s Disease, and there appear to be limited treatment options. Can anyone provide some guidance on this issue?

The No 1 answer:

Answer by peqli
the only definitive cure for lung cancer is through surgery, however it is not done on everyone, as not everyone is a suitable candidate

i would presume your friend is in the 60-70 age group, which is not a really the best age to have radical surgery (as it is a major surgery and may involve removing the whole affected lung) and taking additional chemotherapies or radiotherapies to increase the effectiveness of the surgery would make the experience much worse. and with the cancer already at an advanced stage, makes the doctor to tend to steer away from the surgical option.

even so, sometimes with radiotherapy or chemotherapy the tumor may shrink and downstage the tumor that the surgeons might consider surgery as an option later along the course

How about adding your own answer to the comments below!

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A question from Teresa S: How likely is a sibling of a Parkinson’s Disease patient to have same diagnosis?
My sister who is 64 has just been diagnosed with Parkinson’s Disease. How likely or what are the chances that me or our other sisters have the same?
How does one get Parkinson’s? I have a Fibromyalgia, which has some similarities in diagnoses. Is it possible/likely for me to have Parkinson’s later in life, as I’m in my 40′s now.?

Most detailed answer:

Answer by GamesGeek
PD traditionally has been considered a non-genetic disorder, however at least between 5 and 10% of the patients are now known to have monogenic forms of the disease. Other genes act as risk factors for sporadic cases of the disease.

What do you think? Leave you answer below!

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